LOKSEWA

Instructions : Each question is multiple choice question , total questions 100 and total time 100 minutes. Short multiple choice questions are 100 points (each question has 1 point) Note: for wrong answer 20 % (0.2) mark will be deducted. 
 


Note: Type correct option (a , b, c or d ) in box then press ckeck button. Note: for wrong answer 20 % (0.2) mark will be deducted.

1.The hiatus semilunaris is seen in ?

(a) Sphenoethmoidal recess

(b) Middle meatus

(c) Superior meatus

(d) Inferior meatus

Ans1:


2.Recurrent laryngeal nerve supplies all of the following except ?

(a) Cricothyroid

(b) Posterior cricoarytenoids

(c) Transverse arytenoids

(d) Anterior cricoarytenoids

Ans2:


3.The adductors of the vocal cords are ?

(a) Transverse arytenoids

(b) Posterior cricoarytenoids

(c) Anterior cricoarytenoids

(d) Cricothyroid

Ans3:


4.Which of the following structure is not seen in posterior triangle of neck ?

(a) Accessory nerve

(b) Posterior belly of omohyoid

(c) Stylohyoid

(d) Superficial cervical artery

Ans4:


5.Which of the following is an example of hinge joint ?

(a) Wrist

(b) Elbow

(c) Metacarpophalangeal joint

(d) Atlantoaxial

Ans5:


6.Which of the following structure does not pass through esophageal hiatus ?

(a) Thoracic duct

(b) Vagus

(c) Left gastric artery

(d) Esophagus

Ans6:


7.Which of the following is not a K dependent factor ?

(a) VIII

(b) Fibrinogen

(c) X

(d) Factor II

Ans7:


8.The motor unit consists of ?

(a) All muscle fibers in a muslce

(b) Motor nerve and muslce fibers that it supplies

(c) Afferent neuron center and efferent neuron

(d) Single muslce fiber and all neurons that innervate it

Ans8:


9.The pH of extracellular fluid is ?

(a) 8

(b) 6

(c) 7.4

(d) 5.5

Ans9:


10.Which of the following is a high energy compound ?

(a) ANP

(b) Adenosine triphosphate

(c) UTP

(d) GTP

Ans10:

11.Which of the following cell types is most common in islets of Langerhans of pancreas ?

(a) Beta cells

(b) Alpha cells

(c) Delta cells

(d) F cells

Ans11:


12.In nephrotic syndrome which of the following is increased ?

(a) Albumin

(b) Ceruloplasmin

(c) Fibrinogen

(d) Transferrin

Ans12:


13.All of the following diseases are transmitted in autosomal recessive pattern except ?

(a) Hurler's syndrome

(b) Hunter syndrome

(c) Alkaptonuria

(d) Gaucher's disease

Ans13:


14.Which of the following protein present in glomerular basement membrane is responsible for charge dependent filtration ?

(a) Proteoglycan

(b) Fibronectin

(c) Albumin

(d) Collagen

Ans14:


15.Which of the following type of nephrotic syndrome does not respond well to steroid therapy ?

(a) Lupus nephritis

(b) Focal segmental glomerulosclerosis

(c) Membranous glomerulonephritis

(d) Membranoprolifertive glomerulonephritis

Ans15:


16.Aplastic crisis is associated with ?

(a) Rubella

(b) Arena virus

(c) SV 40

(d) Parvovirus B19

Ans16:


17.Which of the following is an agglutination test ?

(a) VDRL

(b) ABO incompatibility

(c) FTA antibody test

(d) Weil Felix

Ans17:


18.Which of the following is false regarding Streptococcus?

(a) Group B Streptococcus lives in female genital tract

(b) Group B Streptococcus causes neonatal meningitis

(c) Group C Streptococcus does not cause any human infection

(d) Classification by Lancefield is based on carbohydrate antigen

Ans18:


19.Which of the following is urease negative ?

(a) Klebsiella

(b) E. coli

(c) Proteus

(d) Enterobacter

Ans19:

20.Anoxic hypoxia is because of ?

(a) Decreased pO2 in arterial blood

(b) Increased pO2 in arterial blood

(c) Increased pCO2 in blood

(d) Increased pO2 in venous blood

Ans20:


21.Best stimulus for secretion of secretin ?

(a) Proteins

(b) Acid

(c) Carbohydrates

(d) Fat

Ans21:


22.Which of the following keton bodies ?

(a) 6 - 12 mmHg (50-180 mmH2O)

(b) 10 - 12 mmHg

(c) 1 - 6 mmHg

(d) 9 - 10 mmHg

Ans22:


23.Plasma membrane is chiefly made up of ?

(a) Phospholipids

(b) Protein

(c) Cholesterol

(d) Carbohydrate

Ans23:


24.Primary motor area for shivering is ?

(a) Dorsomedial posterior hypothalamus

(b) Ventromedial anterior hypothalamus

(c) Red nucleus

(d) Motor cortex

Ans24:


25.Which of the following has highest pH ?

(a) Pancrease

(b) Gastric juice

(c) Gallbladder bile

(d) Saliva

Ans25:


26.Which of the following is true ?

(a) ECF is rich in K+

(b) ECF has high Na+:K+ ratio

(c) ECF is more than ICF

(d) ECF is rich in organic anion

Ans26:


27.Which of the following amino acid is ketogenic ?

(a) L lysine

(b) Arginine

(c) Leucine

(d) Methionine

Ans27:


28.Purely ketogenic amino acid ?

(a) Proline

(b) Tyrosine

(c) Leucine

(d) Phenylalanine

Ans28:

29.Which of the following enzymes is deficient in galactosemia ?

(a) Epimerase

(b) Hexokinase

(c) Galactose-1-phosphate uridyl transferase

(d) Hormone sensitive lipase

Ans29:


30.Fluoride inhibits which of the following in the glycolysis ?

(a) Succinate dehydrogenase

(b) Cis-aconitase

(c) Enolase

(d) Malonate

Ans30:


31.The activity of the following enzymes is affected by biotin deficiency ?

(a) Transketolase

(b) Dehydrogenase

(c) Oxidase

(d) Carboxylase

Ans31:


32.Dietary fiber is ?

(a) Rich in collagen

(b) Rich in starch

(c) Rich in pectin

(d) Rich in proteoglycans

Ans32:


33.In muscular dystrophy, the characteristic finding is ?

(a) Inflammatory cell infiltrate

(b) Muscle necrosis

(c) Heterogenicity of muscle fiber

(d) Nuclear proliferation beneath sarcolemma

Ans33:


34.The liver change in Reye's syndrome is ?

(a) Cirrhosis

(b) Diffuse steatosis

(c) Chronic hepatitis

(d) Acute hepatitis

Ans34:


35.Cystic fibrosis is inherited as ?

(a) AD

(b) AR

(c) X-linked recessive

(d) X-linked dominant

Ans35:


36.Gynecomastia is not associated with ?

(a) Ca++ channel antagonists

(b) Estrogen therapy

(c) Carcinoid syndrome

(d) Chronic liver disease

Ans36:


37.CEA is a tumor marker of carcinoma of ?

(a) Gonadal germ cell tumor

(b) Hepatocellular carcinoma

(c) Colon

(d) Liver

Ans37:

38.Which of the following is false regarding Cryptococcus neoformans ?

(a) It causes superficial skin infection

(b) It is urease negative

(c) It has 4 serotypes

(d) It grows at 37 C

Ans38:


39.Which of the following is not transmitted by ingestion of its eggs ?

(a) Hydatid disease

(b) Ascariasis

(c) Trichuriasis

(d) Strongyloides

Ans39:


40.In which of the following man is the intermediate host ?

(a) Wuchereria bancrofti

(b) Dracunculus medinensis

(c) Echinococcus granulosus

(d) Taenia solium

Ans40:


41.Which of the following is true regarding Giardia ?

(a) Both cyst and trophozoites are found

(b) Cause mucosal invasion

(c) CFT is the diagnostic test

(d) Normal habitat is large intestine

Ans41:


42.In coronary artery disease the role of beta-blocker in decreasing the symptoms is by ?

(a) Preventing exercise induced tachycardia

(b) Decreasing cardiac force

(c) Increasing the coronary blood flow

(d) Decreasing heart rate

Ans42:


43.A 60-year-old man taking opium for 20 years stops its consumption suddenly and presents after 2 days. Which of the following is likely to occur due to withdrawal ?

(a) Drowsiness

(b) Rhinorrhea

(c) Pupillary constriction

(d) Hypotension

Ans43:


44.All of the following are selective beta-blockers except ?

(a) Atenolol

(b) Metoprolol

(c) Bisoprolol

(d) Propranolol

Ans44:


45.Steroids cause all the following except ?

(a) Hypertrophy of muscle

(b) Hypokalemia

(c) Neuropsychiatric symptoms

(d) Hyperglycemia

Ans45:


46.The drugs causing pancreatitis acutely are all except ?

(a) Methyldopa

(b) Valproate

(c) Furosemide

(d) Somatostatin

Ans46:

47.Renal toxicity of aminoglycosides does not increase with ?

(a) Advanced age

(b) Hypokalemia

(c) Concomitant penicillin administration

(d) Prior aminoglycoside therapy

Ans47:


48.Which of the following is false regarding anti-arrhythmic ?

(a) Amiodarone belongs to class III and acts by prolonging APD

(b) Verapamil belongs to class II and acts by blocking fast Na+ channel

(c) Mexiletine belongs to class Ib and acts by decreasing refractory period

(d) Quinidine belongs to class Ic and acts by prolonging APD

Ans48:


49.Oculogyric crisis is known to be produced by all of the following drugs, except ?

(a) Trifluoperazine

(b) Atropine

(c) Prochlorperazine

(d) Perphenazine

Ans49:


50.The following drugs have significant drug interaction with digoxin, except ?

(a) Cholestyramine

(b) Thiazide diuretics

(c) Quinidine

(d) Amlodipine

Ans50:


51.One of the following is not true about nesiritide ?

(a) It is a brain natriuretic peptide analogue

(b) It is used in acutely decompensated heart failure

(c) It has significant oral absorption

(d) It has a short half-life

Ans51:


52.The following statements regarding finasteride are true, except ?

(a) It is used in the medical treatment of benign prostatic hypertrophy (BPH)

(b) Impotence is well documented after its use

(c) It blocks the conversion of dihydrotestosterone to testosterone

(d) It is a 5-alpha-reductase inhibitor

Ans52:


53.Enternacept acts by one of the following mechanisms ?

(a) By blocking tumor necrosis factor

(b) By blocking bradykinin synthesis

(c) By inhibiting cycloxygenase-2

(d) By blocking lipoxygenase

Ans53:


54.Which of the following reaction in glycolysis is not reversible ?

(a) Triose-phosphate-isomerase

(b) Phosphofructokinase

(c) Dehydrogenase

(d) Phosphoglycerate mutase

Ans54:


55.How many kinases are involved in glycolysis ?

(a) 2

(b) 4

(c) 5

(d) 1

Ans55:

56.All of the following hormones have cell surface receptors, except ?

(a) Adrenalin

(b) Growth hormone

(c) Insulin

(d) Thyroxine

Ans56:


57.Fluoride used in the collection of blood samples for glucose estimation, inhibits the enzyme ?

(a) Glucokinase

(b) Hexokinase

(c) Enolase

(d) Glucose-6-phosphatase

Ans57:


58.Ladder pattern of DNA electrophoresis in apoptosis is caused by the action of the following enzyme ?

(a) Endonuclease

(b) Transglutaminase

(c) DNAse

(d) Caspase

Ans58:


59.The membrane protein, clathrin is involved in ?

(a) Cell motility

(b) Receptor mediated endocytosis

(c) Exocytosis

(d) Cell shape

Ans59:


60.The amino acid residue having an imino side chain is ?

(a) Lysine

(b) Histidine

(c) Tyrosine

(d) Proline

Ans60:


61.In which of the following organ, liquefactive necrosis is commonly found ?

(a) Liver

(b) Brain(CNS)

(c) Heart

(d) Lung

Ans61:


62.In parotid tumor, perineural infiltration is seen in ?

(a) Adenoid cystic carcinoma

(b) Adenolymphoma

(c) Mixed parotid tumor

(d) Cylindrioma

Ans62:


63.Most common intracranial tumor is ?

(a) Glioma

(b) Medulloblastoma

(c) Meningioma

(d) Secondaries

Ans63:


64.Gitter cells are ?

(a) Oligodendrocytes

(b) Phagocytes in central nervous system

(c) Epidermal cells

(d) Astrocytes

Ans64:

65.Which of the following carcinoma of lung secretes PTH like substance ?

(a) Anaplastic type

(b) Large cell

(c) Squamous cell

(d) Oat cell

Ans65:


66.Whichof the following is not involved in Sipple's syndrome or MEN type IIA ?

(a) Thyroid

(b) Parathyroid

(c) Pituitary

(d) Adrenal

Ans66:


67.Which of the following is not decreased in nephrotic syndrome ?

(a) Ceruloplasmin

(b) Fibrinogen

(c) Transferrin

(d) Albumin

Ans67:


68.Cytokeratin is a marker for ?

(a) Carcinoma

(b) Adenoma

(c) Lymphoma

(d) Sarcoma

Ans68:


69.Rosette arrangement of cell is present in ?

(a) Leydig cell tumor

(b) Retinoblastoma

(c) Lymphosarcoma

(d) Mesothelioma

Ans69:


70.Positive Schick test indicates ?

(a) Immunity to diphtheria

(b) Susceptibility to diphtheria

(c) Hypersensitivity to diphtheria

(d) Infection with diphtheria

Ans70:


71.Not a STD ?

(a) Echinococcus

(b) Hepatitis B

(c) Group B Streptococcus

(d) Candida

Ans71:


72.Retrovirus have ?

(a) ds DNA

(b) Segmented DNA

(c) Reverse transcriptase

(d) DNA polymerase

Ans72:


73.Infectivity of chickenpox lasts for ?

(a) 3 days after onset of rash

(b) 6 days after onset of rash

(c) Till the last scab falls off

(d) Till the fever subsides

Ans73:

74.In salmonellosis isolation is done till ?

(a) Three consecutive negative stool cultures

(b) Fever subsides

(c) Spleen subsides

(d) Blood culture negative

Ans74:


75.Secular trend refers to ?

(a) Change of pattern over a long period of time

(b) Change of pattern over a short period of time

(c) Gradual change in a particular direction

(d) Decrease in prevalence of disease

Ans75:


76.Prevalence rate of leprosy is not high in the state of ?

(a) Uttar Pradesh

(b) West Bengal

(c) Orissa

(d) Maharashtra

Ans76:


77.Most common indirect cause of maternal mortality in our country is ?

(a) Hemorrhage

(b) Anemia

(c) Heart disease

(d) Infection

Ans77:


78.In multiple myeloma the amyloid protein is ?

(a) AL

(b) AA

(c) SAA

(d) b2M

Ans78:


79.Pseudopolyposis are seen in ?

(a) Ulcerative colitis

(b) Crohn's disease

(c) Coeliac sprue

(d) Whipple's disease

Ans79:


80.Most common cause of SVC obstruction is ?

(a) Bronchogenic carcinoma

(b) Fibrosis of SVC

(c) Pericardial fibrosis

(d) Hepatocellular carcinoma

Ans80:


81.About 90% of CO2 are carried in the blood as ?

(a) Dissolved CO2

(b) Bicarbonate

(c) Carbamino compound

(d) Carboxyhemoglobin

Ans81:


82.Maximum absorption of water occurs in ?

(a) PCT

(b) DCT

(c) Loop of Henle

(d) Collecting tubules

Ans82:

83.Which of the following viruses cannot be grown in cell culture ?

(a) Rotavirus

(b) Enterovirus 70

(c) Coxsackie virus

(d) Echovirus

Ans83:


84.Which of the following is false regarding diphtheria toxin ?

(a) Toxin is necessary for local wound production

(b) Iron is critical for toxin production

(c) Beta lysogenic strain produces toxin

(d) Toxin blocks elongation of protein

Ans84:


85.Memory T cells can be identified by using the following marker ?

(a) CD45RA

(b) CD45RB

(c) CD45RC

(d) CD45RO

Ans85:


86.Floppy baby syndrome may occur due to ?

(a) Clostridium botulinum

(b) Clostridium welchii

(c) Clostridium tetani

(d) Clostridium difficile

Ans86:


87.Which of the following cells is known as large granular lymphocyte (LGL) ?

(a) Plasma cells

(b) NK cells

(c) T cells

(d) Autograft

Ans87:


88.The chances of isolating viable spirochetes are least in ?

(a) Gumma

(b) Rash

(c) Condyloma

(d) Chancre

Ans88:


89.Streptococcal toxin shock syndrome is due to which of the following virulence factors ?

(a) M protein

(b) Pyrogenic exotoxin

(c) Streptolysin O

(d) Carbohydrate cell wall

Ans89:


90.Corneal scraping of a patient reveals narrow angled septate hyphae. Most likely etiologic agent is ?

(a) Aspergillus fumigatus

(b) Mucor

(c) Candida albicans

(d) Histoplasma capsulatum

Ans90:


91.Which of the following is not true of Diplococcus pneumoniae ?

(a) Bile solubility

(b) Optochin resistance

(c) Causes meningitis

(d) Possess capsule

Ans91:

92.Complement fixation is maximum by ?

(a) IgG

(b) IgA

(c) IgM

(d) IgE

Ans92:


93.HIV virus belongs to family ?

(a) Lentivirus

(b) Flavivirus

(c) Oncovirinae

(d) Picornavirus

Ans93:


94.El-Tor Vibrio was first found in ?

(a) Indonesia

(b) India

(c) Bangladesh

(d) Spain

Ans94:


95.Which of the following is involved in amyotrophic lateral sclerosis ?

(a) Raphae nucleus

(b) Lower motor neuron

(c) Posterior column

(d) Anterior and posterior column

Ans95:


96.Which of the following is false regarding oxytocin ?

(a) It causes milk ejection reflex

(b) It is least sensitive to uterus in pregnancy

(c) May also involved in luteolysis

(d) It triggers increase in intracellular level of Ca++

Ans96:


97.EDRF simulates ?

(a) The action of cAMP

(b) The action of nitric oxide

(c) The action of halothane

(d) The action of ether

Ans97:


98.Starling's principle is ?

(a) Muscle fiber length does not affect contraction

(b) Contraction is proportional to blood flow

(c) Within physiological limits, the force of contraction is proportional to initial length of cardiac muscle fiber

(d) Energy of contraction is proportional to afterload

Ans98:


99.In substantia nigra, the major neurotransmitter is ?

(a) Dopaminergic

(b) Acetylcholine

(c) Noradrenaline

(d) GABA

Ans99:


100.Antidromic conduction is seen in ?

(a) Axon

(b) Synapse

(c) Both

(d) None

Ans100:

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